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What Is Idiopathic Hypersomnia? - Hypersomnia Foundation

The Hypersomnia Foundation engages, informs & champions our global community to improve the lives of people with idiopathic hypersomnia & related sleep disorders, including narcolepsy and Kleine-Levin syndrome.

Categories: Health, Health and Wellness
Topics: hypersomnia foundation, what is idiopathic hypersomnia?

Moz DA: 44 Moz Rank: 4 Semrush Rank: 209,459 Facebook ♡: 2,168

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sleepmedicine.com
Ohio Sleep Medicine Institute | Comprehensive Accredited Sleep Disorders Center in Columbus, Ohio | Treatment for Sleep Apnea, Snoring and Other Sleep Disorders
Receive treatment for sleep apnea, snoring, excessive sleepiness, insomnia, restless legs syndrome or other sleep disorders from board-certified sleep specialists Dr. Asim Roy and Dr. Markus Schmidt - Voted 2010 Top Sleep Medicine Doctor in Central Ohio, Columbus Monthly

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wakeupnarcolepsy.org
Wake Up Narcolepsy | Awareness. Research. Support.
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narcolepsynetwork.org
Narcolepsy Network - Benefits and services for people with Narcolepsy
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narcolepsy.org.uk
Narcolepsy UK |
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xyremhcp.com
XYREM®—Treatment for Narcolepsy With Cataplexy and/or Excessive Daytime Sleepiness
Healthcare professionals can find information about XYREM® (sodium oxybate), a treatment for cataplexy and/or excessive daytime sleepiness (EDS) in narcolepsy for adults and pediatric patients ages 7 and older. See XYREM® prescribing information & BOXED Warning about serious side effects, CNS depression, misuse and abuse.

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hypersomnolenceaustralia.org.au
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Hypersomnolence Australia advocates, educates and raises awareness of the neurological sleep/wake disorder Idiopathic Hypersomnia (Hypersomnolence) Find out more.

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sleep-journal.com
Sleep Medicine | Journal | ScienceDirect.com by Elsevier
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sleepmedres.org
Sleep Medicine Research
Sleep Medicine Research (Sleep Med Res) is an official journal of the Asian Society of Sleep Medicine (ASSM), Korean Society of Sleep Medicine (KSSM), and Korean Society of Sleep Research, published two times in June and December. The journal aims to contribute to the better understanding of sleep physiology and sleep disorders. Sleep Medicine Research covers both basic and clinical contributions relevant to physiology or pathophysiology of normal sleep and full spectrum of sleep disorders including sleep apnea, insomnia, circadian rhythm disorders, sleep movement disorders, parasomnia, sleep deprivation. Original results from basic sleep science and related topics in medical, neurologic, psychiatric, dental, surgical, and public health fields are also included. Papers, to be accepted, will include original article (clinical and basic sleep research), review articles, brief communications (including case reports), images in sleep medicine, and letters to the editor.

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American Academy of Sleep Medicine | AASM | Sleep | Medical Society
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Alternative model for Alzheimer’s neurodegeneration
In recent debate over the FDA’s approval of the Alzheimer’s drug aducanumab, we’ve heard a lot about the “amyloid hypothesis.” In that context, it’s refreshing to learn about a model of Alzheimer’s neurodegeneration that doesn’t start with the pathogenic proteins amyloid or Tau. Instead, a new paper in Alzheimer’s & Dementia from Emory neuroscientist Shan Ping Yu and colleagues focuses on an unusual member of the family of NMDA receptors, signaling molecules that are critical for learning and memory. Their findings contain leads for additional research on Alzheimer’s, including drugs that are already FDA-approved that could be used preventively, and genes to look at for risk factors. “It’s not just another rodent model of Alzheimer’s,” Yu says. “We are emphasizing a different set of mechanisms leading to neurodegeneration.” Those mechanisms include alterations in calcium and neuronal hyperactivity, which occur first in this mouse model, rather than standard models that have clumps of amyloid or Tau as the primary drivers. GluN3A (in the diagram, NR3) is an inhibitory subunit within NMDA receptor assemblies, which function as glutamate-gated cation channels. GluN3A is a key regulator of neuronal activity and calcium homeostasis in both early and late life. For the last several years, Yu and his laboratory have been studying the NMDA receptor subunit GluN3A in the context of stroke and also brain development. According to their research, GluN3A acts like a control rod in a nuclear reactor, cooling down signaling in the brain so that things don’t overheat. It’s an inhibitory part of a receptor assembly that is usually stimulatory. Yu says GluN3A’s role in the adult brain is understudied, because it is generally thought to fade away after early development. Mice that are missing the gene for GluN3A get a benefit earlier in life, in that they have enhanced memory and spatial learning. But later on, the missing gene’s function catches up, and th

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