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DNA Direct provides professional paternity, maternity, sibling and relationship DNA services with an easy to use ordering process and downloadable results. . DNA-directed RNA interference (DRNAI) is a gene-silencing technique that utilizes DNA constructs to activate an animal cell's endogenous RNA interference (RNAI) pathways. DNA constructs are designed to express self-complementary double-stranded RNAs, typically short-hairpin RNAs , that once processed bring about silencing of a target gene or genes. Any RNA including endogenous messenger RNA (mRNAs) or viral RNAs, can be silenced by designing constructs to express double-stranded RNA complementary to the desired mRNA target. This mechanism has been demonstrated to work as a novel therapeutic to silence disease-causing genes across a range of disease models, including viral diseases such as HIV, hepatitis B or hepatitis C, or diseases associated with altered expression of endogenous genes such as drug-resistant lung cancer, neuropathic pain, advanced cancer, and retinitis pigmentosa. https://en.wikipedia.org/wiki/DNA-directed_RNA_interference

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