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Home │ NERLYNX® (neratinib) tablets

NERLYNX is a prescription medicine used alone to treat adults who have early-stage HER2+ breast cancer. NERLYNX is also used with capecitabine to treat adults who have HER2+ metastatic breast cancer. Explore available services and support, sign up for updates specific to you.

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Topics: (neratinib) tablets, home │ nerlynx®

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Puma Biotechnology
Puma Biotechnology, Inc. is a biopharmaceutical company dedicated to the acquisition, development and commercialization of novel therapeutics for the treatment of cancer. Puma in-licenses the global development and commercialization rights to PB272 (neratinib, oral), PB272 (neratinib, intravenous) and PB357. Neratinib, oral was approved by the U.S. Food and Drug Administration (FDA) in 2017 for the extended adjuvant treatment of adult patients with early stage HER2-overexpressed/amplified breast cancer, following adjuvant trastuzumab-based therapy, and is marketed in the United States as NERLYNX� (neratinib) tablets. In February 2020, NERLYNX was also approved by the FDA in combination with capecitabine for the treatment of adult patients with advanced or metastatic HER2-positive breast cancer who have received two or more prior anti-HER2-based regimens in the metastatic setting. NERLYNX was granted marketing authorization by the European Union in 2018 for the extended adjuvant treatment of adult patients with early stage hormone receptor-positive HER2-overexpressed/amplified breast cancer and who are less than one year from completion of prior adjuvant trastuzumab-based therapy. Puma�s licensing partners have also received marketing authorization to commercialize NERLYNX in Canada, Israel, and several countries in Europe, Greater China, South America and Southeast Asia. NERLYNX� is a registered trademark of Puma Biotechnology, Inc. Puma Biotechnology was founded by Alan Auerbach in 2010 and is headquartered in Los Angeles, California. Mr. Auerbach previously founded and served as Chief Executive Officer and President of Cougar Biotechnology, Inc., a company dedicated to in-licensing and developing drugs for the treatment of cancer. Cougar was acquired by Johnson & Johnson in July 2009 for approximately $1 billion. Additional information may be found at www.pumabiotechnology.com.


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We are Havas Lynx Group. A leading global healthcare communications agency, devoted to changing the way the world does healthcare communications.


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Person appointed by a state to conduct diplomacy with another state or international organization. A diplomat (from Ancient Greek: δίπλωμα; romanized diploma) is a person appointed by a state or an intergovernmental institution such as the United Nations or the European Union to conduct diplomacy with one or more other states or international organizations. The main functions of diplomats are: representation and protection of the interests and nationals of the sending state; initiation and facilitation of strategic agreements; treaties and conventions; promotion of information; trade and commerce; technology; and friendly relations. Seasoned diplomats of international repute are used in international organizations (for example, the United Nations, the world's largest diplomatic forum) as well as multinational companies for their experience in management and negotiating skills. Diplomats are members of foreign services and diplomatic corps of various nations of the world. The sending state is required to get the consent of the receiving state for a person proposed to serve in key diplomatic positions such as an ambassador, also referred to as the head of the mission.

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