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Focus on your science. Access data, run analysis tools, and collaborate in Terra.Bio a scalable platform for biomedical research. Telomeric repeat-containing RNA. TERRA in biology is an abbreviation for "TElomeric Repeat-containing RNA". TERRA is RNA that is transcribed from telomeres — the repeating 6-nucleotide sequences that cap the ends of chromosomes. TERRA functions with shelterin to inhibit telomere lengthening by enzyme telomerase.TERRAs are essential for telomere length and maintenance. At least four factors contribute to telomere maintenance: telomerase, shelterin, TERRA and the CST Complex.TERRA can also regulate telomere length by increasing euchromatin formation. On the other hand, nonsense-mediated decay factor enrichment at telomeres may exist to prevent TERRA inhibition of telomerase. https://en.wikipedia.org/wiki/TERRA_(biology)
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